As you can imagine, traveling by train between Italy’s two international centers is an easy and efficient experience. Many of Italy’s high-speed trains make the 297-mile journey in just 3 hours and 3 minutes.
Get ready to experience some truly remarkable scenery as you ride south through Italy’s Lombardy, Emilia-Romagna and Tuscany regions. Many trains stop in Bologna, Padua or Genoa en route to Rome. On the faster routes, you won’t be required to change trains. However, if you’re traveling on a slower and less expensive regional train, you may be required to transfer from one train to another.
Milan to Rome train times
High-speed trains leave Milano Centrale once or twice per hour for Rome's Termini station — averaging 90 trains per day. The earliest train leaves Milano Centrale at 5:00 a.m. The last train to Rome leaves Milan at 11:18 p.m.
Note that weekends and holidays typically mean less frequent service and sometimes longer travel times.
Amenities on the train between Milan and Rome
Many trains make the daily journey between Milan and Rome in just 3 hours and 3 minutes, traveling up to 155 miles per hour.
Italy’s high-speed trains are equipped with air conditioning and electrical outlets at your seat to charge devices. There is wifi on trains, but the signal will drop in tunnels and at stations. Expect a cafe car on every train, as well as food cart that brings snacks, sandwiches and beverages to your seat. At the end of each car you’ll find a restroom and plenty of racks to store large luggage.
Located at the northern end of the city center, Milan Centrale is a hub for Milan’s Metro, tram and bus networks. Here you can catch high-speed trains to Italian and international destinations, as well as inter-city and regional trains to smaller cities and towns. Milan Central is also the destination for the Malpensa Express, which goes to Milan’s main airport.
Termini is Rome’s large, international train station and the main transportation hub for public transportation in Rome. Located in the center of the city, Roma Termini provides daily service to all major Italian cities as well as many major European cities. From Termini you can also catch the Leonardo Express train to Rome’s Leonardo da Vinci-Fiumicino airport.