Train from Pisa to Rome


Venture between two of Italy’s most famous monuments, the Leaning Tower and the Colosseum. Learn about taking the train from Pisa to Rome.

Pisa and Rome are quite different Italian cities, though each is home to one of the country’s most visited attractions. It’s not surprising, then, that the two cities are easily reached ny Italy’s robust rail network.

Many of the train routes from Pisa to Rome require changing trains in Florence, though there are some direct routes as well. Either way, taking the train takes less time and involves far less of a hassle than driving the 220 miles (354 km) covered by the train.

Frequent Trains from Pisa to Rome

The high-speed Alta Velocità (AV) train serve both Pisa and Rome via the Frecciabianca line, the third-tier of the AV trains. The two stations are also connected by the slower InterCity trains. Frecciabianca trains travel from Pisa Centrale station to Roma Termini station in as little as 2 hours and 35 minutes, while the InterCity trains can take over 3.5 hours.

The indirect option requires changing trains along the way, almost always at Firenze Santa Maria Novella station in Florence. These trips range from 2 hours and 45 minutes to 3 hours and 20 minutes, and involve taking a Regionale or Regionale Veloce train from Pisa to Florence, followed by an AV train from Florence to Rome.

Should you prefer the Italo network, your only option is to take a Trenitalia Regionale or Regionale Veloce train from Pisa into Florence, and then an Italo train to Rome. Italo connects Santa Maria Novella with both Roma Termini and Roma Tiburtina stations, which takes up to 1.5 hours.

There are 75 trains per day traveling from Pisa to Rome, including routes that require a change in Florence. The first leaves Pisa at 5:45am and the last at 8:51pm. Direct trains run roughly every other hour from Pisa to Rome, whereas routes that require a transfer in Florence run up to four times per hour. Ticket prices on this route range from $28-56.

Note that weekends and holidays typically mean less frequent service and sometimes longer travel times.

Direct Trains from Pisa to Rome

Most of the trains linking Pisa with Rome are not direct, and require a train transfer in Florence. Even if changing trains, the indirect route is only 10-20 minutes longer than a direct train, so you can select an itinerary that suits you rather than focusing only on the direct trains. If you’d prefer a durect train, be sure you’re looking only at the “Direct Trains” option when you search on our site.

Amenities on Trains from Pisa to Rome

The top of the line AV trains are Frecciarossa, and these train cars are all equipped with air-conditioning and power outlets in your seat for your convenience. There are both 1st-class and 2nd-class cars. First class passengers get a free drink and a choice of newspaper). A cafe car is available to all passengers.

On the Frecciabianca trains, there are also both 1st-class and 2nd-class cars. As with Frecciarossa trains, 1st-class passengers get a free drink and a newspaper. Frecciabianca trains sometimes have a cafe car which all passengers can use, and power outlets are in both class cars at each seat.

Pisa, Florence, and Rome Train Stations

Pisa Centrale station is the city's primary station, located 1.4 miles (2.3 km) from some of the main attractions, including the leaning tower and cathedral. There is a luggage storage office at the station if you need to store your bags while you make a quick trip to see the tower. Take the No. 1 bus from the station to get to the Campo dei Miracoli.

Rome's Termini station is the city's largest train station, and also a major transportation hub within Rome. Many bus lines stop right outside the station, and there is also a Metro station inside Termini.

If you have a train transfer in Florence, you'll be at Santa Maria Novella station (sometimes abbreviated as S.M. Novella). It's close to much of the historic center, as well as a big hub for buses, so if you have some time to kill between trains and want to do a little sightseeing in the Tuscan capital it's relatively easy to do so. The luggage storage office is located on the ground floor.

Journey Information

See below for details on traveling from Pisa to Rome by train.

Frequently Asked Questions (FAQs) About Train Travel in Italy

From seat assignments and luggage space to the different types of tickets, here are some of the most frequently asked questions about train travel in Italy.

Arrival and Departure Train Destinations

Read on for information about Pisa to Rome train stations.

Pisa Centrale Guide

Pisa Centrale  Guide

Pisa's main train station, with its grand archways, is also one of the central rail hubs for Tuscany, with 16 platforms.


Rome Termini Guide

Rome Termini  Guide

Rome's transportation mecca boasts countless amenities and connections for Italy's rail passengers. One special amenity is ItaliaRail's very own VIP station oasis, the ItaliaPass Lounge, at the start of Track 25.


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